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Different post-translational modifications of the cysteine residue in this ... Open Access
Published: 12 May 2026
Figure 1
Different post-translational modifications of the cysteine residue in this study. Diagram of Cys-PTM used in this study.
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Seven different types of cysteine metal-binding: i) iron–sulphur cluster, i... Open Access
Published: 12 May 2026
Figure 4
Seven different types of cysteine metal-binding: i) iron–sulphur cluster, ii) alkali metal ions, iii) alkaline earth metals, iv) nickel–iron sulphur clusters, v) transition metal ions, vi) a) metallothionein, and vii) heavy metal ions. Each type has several subtypes:— i) a) 3Fe–4S, b) 2Fe–2S, c) 4F
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Heatmap of the cysteine post-translational modifications across various cel... Open Access
Published: 12 May 2026
Figure 8
Heatmap of the cysteine post-translational modifications across various cell organelles, in this study. The figure was generated using Python (version 3.12.3) module seaborn (version = 0.13.2) and matplotlib (version = 3.10.1). Heatmap of Cys-PTMs across cell organelles.
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Sequence motifs around the post-translational sites of different cysteine p... Open Access
Published: 12 May 2026
Figure 9
Sequence motifs around the post-translational sites of different cysteine post-translational modifications among different species: a) disulphide (H. sapiens), b) 4Fe–4S (H. sapiens), c) Zn 2+ (H. sapiens), d) Mn 2+ (A. thaliana), e) Cd 2+ (A. thaliana), f) Mo 2+ (Mus musculus), g) K + (H. sapi
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Simple tree representation of biochemical pathways involving seven Cys-PTMs... Open Access
Published: 12 May 2026
Figure 3
Simple tree representation of biochemical pathways involving seven Cys-PTMs (inwards). The pathway names appearing in >50 cysteine entries are shown for clarity (outwards). The figure was generated using Interactive Tree of Life (iTOL) v7. Simple tree for Cys-PTM related pathways.
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(Left panel)Query: CysDBase Online Webserver page Input: a) General Query S... Open Access
Published: 12 May 2026
Figure 12
(Left panel)Query: CysDBase Online Webserver page Input: a) General Query Section, b) FASTA Sequences Download, and c) protein structural microenvironment. (Right panel) Outputs: d) Biochemical information (tabular form) and e) protein microenvironment. CysDBase homepage.
Journal Article
CysDBase: a comprehensive database of cysteine post-translational modifications across protein sequence, structure, microenvironment, class, cellular localization, biological pathway, and taxonomy Open Access
Database, Volume 2026, 2026, baag021, https://doi.org/10.1093/database/baag021
Published: 12 May 2026
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Schematic representation of dataset curation, database construction, deploy... Open Access
Published: 12 May 2026
Figure 2
Schematic representation of dataset curation, database construction, deployment, and homepage of CysDBase. CysDBase work flow.
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Cysteine cross-talk reported in the CysDBase. The X-axis represents UniProt... Open Access
Published: 12 May 2026
Figure 5
Cysteine cross-talk reported in the CysDBase. The X-axis represents UniProt IDs were followed by residue numbers (UniProt_Residue No.) and the Y-axis represents Cys-PTMs. Cysteine cross-talks in CysDBase.
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Heatmap of the cysteine post-translational modifications across various tax... Open Access
Published: 12 May 2026
Figure 6
Heatmap of the cysteine post-translational modifications across various taxonomic kingdoms, in this study. The figure was generated using Python (version 3.12.3), module seaborn (version 0.13.2), and matplotlib (version 3.10.1). Heatmap of Cys-PTMs across taxonomic kingdoms.
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Heatmap of the cysteine post-translational modifications across enzyme clas... Open Access
Published: 12 May 2026
Figure 7
Heatmap of the cysteine post-translational modifications across enzyme classes, in this study. The figure was generated using Python (version 3.12.3) module seaborn (version 0.13.2) and matplotlib (version = 3.10.1). Heatmap of Cys-PTMs across enzyme classes.
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Three clusters of protein microenvironments (defined by buried fraction [X-... Open Access
Published: 12 May 2026
Figure 10
Three clusters of protein microenvironments (defined by buried fraction [X-axis] and rHpy [Y-axis]) around cysteines reported in this database. Frequencies of each cluster are shown, following the cluster names. A representative subset (10% of the total data points) was used for clustering. Three-di
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Heatmap of the cysteine post-translational modifications across the three m... Open Access
Published: 12 May 2026
Figure 11
Heatmap of the cysteine post-translational modifications across the three microenvironment clusters, in this study. The figure was generated using Python (version 3.12.3) module seaborn (version 0.13.2) and matplotlib (version = 3.10.1). Heatmap of Cys-PTMs across microenvironments.
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MOKCa-3D data processing workflow. This figure shows the overall workflow c... Open Access
Published: 27 April 2026
Figure 1.
MOKCa-3D data processing workflow. This figure shows the overall workflow consisting of four major components. (A) Mutations data processing—collection, filtering, normalization, and mapping of cancer associated mutations from TCGA and UniProt, (B) structural impact analysis—mapping mutations onto 3
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MOKCa-3D web interface. This figure shows user interface for gene-based que... Open Access
Published: 27 April 2026
Figure 3.
MOKCa-3D web interface. This figure shows user interface for gene-based queries to explore cancer-associated mutations or browse set of genes (Oncogene, Tumour-Suppressor, Protein-kinase, Drug-Target genes, DNA damage response proteins). For image description, please refer to the figure legend an
Journal Article
MOKCa-3D database: functional and structural analysis of missense mutations in cancer Open Access
Database, Volume 2026, 2026, baag001, https://doi.org/10.1093/database/baag001
Published: 27 April 2026
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MOKCa-3D overall architectural design. This figure shows the overview of th... Open Access
Published: 27 April 2026
Figure 2.
MOKCa-3D overall architectural design. This figure shows the overview of the MOKCa-3D platform architecture, consisting of MySQL relational database for mutation and annotation data, a Django backend for data processing and API endpoints to deliver data, and ReactJS front-end for interactive visuali
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Searching MOKCa-3D. This figure shows an example of use, analysing mutation... Open Access
Published: 27 April 2026
Figure 4.
Searching MOKCa-3D. This figure shows an example of use, analysing mutations in KRAS. (A) Gene search page—users begin by querying a gene of interest. (B) Gene-level view (example: KRAS)—displays functional annotations (GO terms) and a filterable mutation list. (C) Mutation-level view (example: G12V
Journal Article
Desert Plant Endophyte Genome Database: a curated repository of endophytic bacterial genomes across arid ecosystems Open Access
Database, Volume 2026, 2026, baag020, https://doi.org/10.1093/database/baag020
Published: 16 April 2026
Journal Article
TCMToxDB: a comprehensive database for the toxicological analysis of traditional Chinese medicines Open Access
Database, Volume 2026, 2026, baag019, https://doi.org/10.1093/database/baag019
Published: 16 April 2026
